@article {Woodarchdischild-2021-321604, author = {Rachael Wood and Emma Thomson and Robert Galbraith and Ciara Gribben and David Caldwell and Jennifer Bishop and Martin Reid and Anoop S V Shah and Kate Templeton and David Goldberg and Chris Robertson and Sharon J Hutchinson and Helen M Colhoun and Paul M McKeigue and David A McAllister}, title = {Sharing a household with children and risk of COVID-19: a study of over 300 000 adults living in healthcare worker households in Scotland}, elocation-id = {archdischild-2021-321604}, year = {2021}, doi = {10.1136/archdischild-2021-321604}, publisher = {BMJ Publishing Group Ltd}, abstract = {Objective Children are relatively protected from COVID-19, due to a range of potential mechanisms. We investigated if contact with children also affords adults a degree of protection from COVID-19.Design Cohort study based on linked administrative data.Setting Scotland.Study population All National Health Service Scotland healthcare workers and their household contacts as of March 2020.Main exposure Number of young children (0{\textendash}11 years) living in the participant{\textquoteright}s household.Main outcomes COVID-19 requiring hospitalisation, and any COVID-19 (any positive test for SARS-CoV-2) in adults aged >=18 years between 1 March and 12 October 2020.Results 241 266, 41 198, 23 783 and 3850 adults shared a household with 0, 1, 2 and 3 or more young children, respectively. Over the study period, the risk of COVID-19 requiring hospitalisation was reduced progressively with increasing numbers of household children{\textemdash}fully adjusted HR (aHR) 0.93 per child (95\% CI 0.79 to 1.10). The risk of any COVID-19 was similarly reduced, with the association being statistically significant (aHR per child 0.93; 95\% CI 0.88 to 0.98). After schools reopened to all children in August 2020, no association was seen between exposure to young children and risk of any COVID-19 (aHR per child 1.03; 95\% CI 0.92 to 1.14).Conclusion Between March and October 2020, living with young children was associated with an attenuated risk of any COVID-19 and COVID-19 requiring hospitalisation among adults living in healthcare worker households. There was no evidence that living with young children increased adults{\textquoteright} risk of COVID-19, including during the period after schools reopened.}, issn = {0003-9888}, URL = {https://adc.bmj.com/content/early/2021/03/17/archdischild-2021-321604}, eprint = {https://adc.bmj.com/content/early/2021/03/17/archdischild-2021-321604.full.pdf}, journal = {Archives of Disease in Childhood} }