PT  - JOURNAL ARTICLE
AU  - Nisha Nair
AU  - Matthew Hurley
AU  - Simon Gates
AU  - Patrick Davies
AU  - I-Ling Chen
AU  - Ian Todd
AU  - Lucy Fairclough
AU  - Andrew Bush
AU  - Jayesh Mahendra Bhatt
TI  - Life-threatening hypersensitivity pneumonitis secondary to e-cigarettes
AID  - 10.1136/archdischild-2019-317889
DP  - 2020 Nov 01
TA  - Archives of Disease in Childhood
PG  - 1114--1116
VI  - 105
IP  - 11
4099  - http://adc.bmj.com/content/105/11/1114.short
4100  - http://adc.bmj.com/content/105/11/1114.full
SO  - Arch Dis Child2020 Nov 01; 105
AB  - We report a case of hypersensitivity pneumonitis (HP) in a young person secondary to vaping. He presented with a putative diagnosis of asthma and required extracorporeal membrane oxygenationbecause of intractable respiratory failure. He developed a critical illness and steroid myopathy and required prolonged rehabilitation. Our patient fulfils diagnostic criteria for HP secondary to e-cigarettes with a positive exposure history, deterioration after skin prick testing, specific serum IgM antibodies against the implicated liquid raising the possibility that the relevant antigen was present in that liquid and radiological and histopathological features compatible with acute HP. There are two learning points. The first is always to consider a reaction to e-cigarettes in someone presenting with an atypical respiratory illness. The second is that we consider e-cigarettes as ‘much safer than tobacco’ at our peril.