PT  - JOURNAL ARTICLE
AU  - Paul MacDaragh Ryan
AU  - Catherine Stanton
AU  - R Paul Ross
AU  - Alan L Kelly
AU  - Eugene Dempsey
AU  - C Anthony Ryan
TI  - Paediatrician’s perspective of infant gut microbiome research: current status and challenges
AID  - 10.1136/archdischild-2019-316891
DP  - 2019 Jul 01
TA  - Archives of Disease in Childhood
PG  - 701--705
VI  - 104
IP  - 7
4099  - http://adc.bmj.com/content/104/7/701.short
4100  - http://adc.bmj.com/content/104/7/701.full
SO  - Arch Dis Child2019 Jul 01; 104
AB  - Due to its innately intriguing nature and recent genomic technological advances, gut microbiome research has been at the epicentre of medical research for over a decade now. Despite the degree of publicisation, a comprehensive understanding and, therefore, acceptance of the area as a whole may be somewhat lacking within the broader medical community. This paper summarises the main analytical techniques and tools currently applied to compositional microbiome research. In addition, we outline five major lessons learnt from a decade of infant microbiome research, along with the current research gaps. Finally, we aim to provide an introduction and general guidelines relating to infant gut microbiome research for the practising paediatrician.