RT Journal Article SR Electronic T1 P275 Denial of vaccination, short way to the epidemic measles JF Archives of Disease in Childhood JO Arch Dis Child FD BMJ Publishing Group Ltd and Royal College of Paediatrics and Child Health SP A140 OP A140 DO 10.1136/archdischild-2017-313273.363 VO 102 IS Suppl 2 A1 Nedelcuta Ramona A1 Calin Gigi A1 Popescu Mirela YR 2017 UL http://adc.bmj.com/content/102/Suppl_2/A140.1.abstract AB Background and aims The National Immunisation Program resulted in a drastic limitation of new cases of infectious and contagious diseases measles, rubella, mumps characteristic of childhood and even eradicate a scourge that polio.Freedom of information and the development of views in the virtual environment came with their negative aspects and many parents refused vaccination and even endangering their own children vaccinated population.Methods It conducted a prospective study over a period of four months, including all cases of measles hospitalised and diagnosed during this period.It took into account age, clinical, laboratory, serological tests, evolution, treatment, complications, hospitalisation time and the duration natural nutrition and the effectuation of vaccinations.Results Were diagnosed 191 patients with measles, most male (114), who had from the beginning cutaneous exanthema and pulmonary disease. Koplik sign was present in 68% of cases.Conclusions Measles appeared mostly in unvaccinated patientsThe appearance vaccinated children raise questions about storage conditions (vaccine administration)Pneumonia that is part of the basic picture of the disease virulence factors raise the issue of changeVirological studies/viral genetic required in outbreak.Legislative code strictly regulated can stop unconscious attitudes.