RT Journal Article
SR Electronic
T1 Developing a paediatric drug formulary for the Netherlands
JF Archives of Disease in Childhood
JO Arch Dis Child
FD BMJ Publishing Group Ltd and Royal College of Paediatrics and Child Health
SP 357
OP 361
DO 10.1136/archdischild-2016-311674
VO 102
IS 4
A1 van der Zanden, Tjitske M
A1 de Wildt, Saskia N
A1 Liem, Yves
A1 Offringa, Martin
A1 de Hoog, Matthijs
YR 2017
UL http://adc.bmj.com/content/102/4/357.abstract
AB As many drugs in paediatrics are used off-label, prescribers face a lack of evidence-based dosing guidelines. A Dutch framework was developed to provide dosing guidelines based on best available evidence from registration data, investigator-initiated research, professional guidelines, clinical experience and consensus. This has clarified the scientific grounds of drug use for children and encouraged uniformity in prescribing habits in the Netherlands. The developed framework and the current content of the Dutch Paediatric Formulary could be used as basis for similar initiatives worldwide, preferably in a concerted effort to ultimately provide children with effective and safe drug therapy.