PT  - JOURNAL ARTICLE
AU  - van der Zanden, Tjitske M
AU  - de Wildt, Saskia N
AU  - Liem, Yves
AU  - Offringa, Martin
AU  - de Hoog, Matthijs
TI  - Developing a paediatric drug formulary for the Netherlands
AID  - 10.1136/archdischild-2016-311674
DP  - 2017 Apr 01
TA  - Archives of Disease in Childhood
PG  - 357--361
VI  - 102
IP  - 4
4099  - http://adc.bmj.com/content/102/4/357.short
4100  - http://adc.bmj.com/content/102/4/357.full
SO  - Arch Dis Child2017 Apr 01; 102
AB  - As many drugs in paediatrics are used off-label, prescribers face a lack of evidence-based dosing guidelines. A Dutch framework was developed to provide dosing guidelines based on best available evidence from registration data, investigator-initiated research, professional guidelines, clinical experience and consensus. This has clarified the scientific grounds of drug use for children and encouraged uniformity in prescribing habits in the Netherlands. The developed framework and the current content of the Dutch Paediatric Formulary could be used as basis for similar initiatives worldwide, preferably in a concerted effort to ultimately provide children with effective and safe drug therapy.