RT Journal Article SR Electronic T1 PS-147 Ultrasound Cardiac Output Monitoring (uscom) In Mechanically Ventilated Critically Ill Children JF Archives of Disease in Childhood JO Arch Dis Child FD BMJ Publishing Group Ltd and Royal College of Paediatrics and Child Health SP A164 OP A164 DO 10.1136/archdischild-2014-307384.442 VO 99 IS Suppl 2 A1 Fremuth, J A1 Kobr, J A1 Pizingerova, K A1 Sasek, L A1 Zamboryova, J YR 2014 UL http://adc.bmj.com/content/99/Suppl_2/A164.1.abstract AB Background and aims Haemodynamic monitoring plays an important role in the management of critically ill patients. The goal of this study was to evaluate haemodynamic changes within first 48 h after initiation of mechanical ventilation (MV). Methods Critically ill children were included and divided into two groups according to the indication for MV. Group A ventilated for pulmonary pathology (P), group B ventilated for non pulmonary pathology (NP). Noninvasive haemodynamic monitoring (USCOM) was used in both groups after the initiation of MV (Time 1) and at 6, 12 and 48 h intervals (Time 2, 3, 4). Parameters such as CI, SVRI, SVI, SBP and DBP were analysed. Strategies of protective MV were applied in both groups. Results Group A included 36 children, mean age 44 months. Group B included 13 children, mean age 58 months. The comparisons within the groups and between the groups are presented in Table 1. View this table:Abstract PS-147 Table 1 Conclusions SVRI increased during first 48 h of ventilation in NP group, SBP increased in both groups. No other clinically significant haemodynamic changes in either group were found. Acknowledgements The work was supported by project PRVOUK P-36.