RT Journal Article
SR Electronic
T1 Serum ferritin and nutritional status: insights from an eating disorders clinic population
JF Archives of Disease in Childhood
JO Arch Dis Child
FD BMJ Publishing Group Ltd and Royal College of Paediatrics and Child Health
SP 221
OP 224
DO 10.1136/archdischild-2012-303272
VO 99
IS 3
A1 Nemba, Kuria
A1 Lewis, Barry
A1 Watson, Hunna
A1 Hoiles, Kimberley
A1 Zhang, Guicheng
A1 Forbes, David
YR 2014
UL http://adc.bmj.com/content/99/3/221.abstract
AB Objective To determine the relationship between serum ferritin and malnutrition in newly assessed patients at a paediatric eating disorders clinic. Design This was a prospectively assessed clinical cohort study. Setting Intake assessment clinic of a tertiary eating disorders service for children and adolescents. Methods Clinical, anthropometric and laboratory features of children and adolescents were systematically measured. The relationship of serum ferritin to other clinical, anthropometric and laboratory measures was determined using linear regression. Results A total of 121 female patients aged 9.5–17.6 years were included, with body mass index (BMI) z score −5.7 to 1.9 (median −1.3). Using multiple regression, serum ferritin was inversely associated with BMI z score (regression coefficient (β)=−0.234, 95% CI −0.413 to −0.055) and serum insulin-like growth factor 1 (IGF-1) (β=−0.476, 95% CI −0.884 to −0.068) and positively associated with alanine aminotransferase (β=0.357, 95% CI 0.055 to 0.659, controlling for age, pubertal stage and serum iron). Conclusions In malnourished adolescents with eating disorders increased serum ferritin is associated with lower BMI z score and serum IGF-1.