TY - JOUR T1 - Investigating microcephaly JF - Archives of Disease in Childhood JO - Arch Dis Child SP - 707 LP - 713 DO - 10.1136/archdischild-2012-302882 VL - 98 IS - 9 AU - C Geoffrey Woods AU - Alasdair Parker Y1 - 2013/09/01 UR - http://adc.bmj.com/content/98/9/707.abstract N2 - 1. Microcephaly is a clinical finding, not a ‘disease’, and is a crude but trusted assessment of intracranial brain volume. 2. Developmental processes reducing in utero neuron generation present at birth with ‘Primary microcephaly’. 3. ‘Secondary microcephaly’ develops after birth and predominantly reflects dendritic or white matter diseases. 4. Microcephalic conditions have a heterogeneous aetiology, but increasingly genomic tests are available that allow an exact diagnosis. ER -