RT Journal Article SR Electronic T1 1358 Effect of Mode of Delivery on Mortality and Morbidity in Very Low Birth Weight Neonates with Respiratory Distress Syndrome JF Archives of Disease in Childhood JO Arch Dis Child FD BMJ Publishing Group Ltd and Royal College of Paediatrics and Child Health SP A387 OP A387 DO 10.1136/archdischild-2012-302724.1358 VO 97 IS Suppl 2 A1 Dursun, A A1 Karagol, BS A1 Hakan, N A1 Karadag, N A1 Zenciroglu, A A1 Okumus, N A1 Dilli, D A1 Beken, S YR 2012 UL http://adc.bmj.com/content/97/Suppl_2/A387.2.abstract AB Background & Aim: It is known that wet lung syndrome and pulmonary maladaptation are more frequent in infants delivered by cesarean section while the effect of mode of delivery on RDS is unknown. In this study, we analyzed the effect of the mode of delivery on RDS outcome in very low birth weight (VLBW) neonates. Methods Data of all the VLBW neonates with respiratory distress syndrome (RDS) between 2007 and 2012 was retrospectively analyzed. Gestational age, gender, birth weight, mode of delivery, necrotizing enterocolitis (NEC), intracranial bleeding (ICH), patent ductus arteriosus (PDA), retinopaty of prematurity (ROP), broncopulmonary dysplasia (BPD) were noted. Results A total of 186 newborns were diagnosed as VLBW neonates with RDS among the 5980 neonates hospitalized in NICU. Mean birth weight and gestational age were 1058±261 grams and 28±2.7 weeks, respectively. Cesarean delivery rate was 62.7%. There were no differences with respect to birth weight, gestational age and gender between mode of delivery. There was no significant relationship between the NEC, PDA, ROP, BPD and mode of delivery. Also no significant relationship between the mode of delivery and mortality was determined. On the other hand, ICH was significantly higher in neonates delivered vaginally (48% vs. 31%, p<0.05). Conclusion Mode of delivery has no effect on the mortality and morbidity of RDS in VLBW neonates but ICH was significantly higher in normal vaginal delivery group. Therefore, mode of delivery should be decided on the basis of obstetrical indications.