RT Journal Article
SR Electronic
T1 909 Analysis of Newborn Screening - Born Exposed to Toxoplasmosis in Pregnancy Alcides Carneiro Hospital in Petropolis - RJ Brazil
JF Archives of Disease in Childhood
JO Arch Dis Child
FD BMJ Publishing Group Ltd and Royal College of Paediatrics and Child Health
SP A260
OP A260
DO 10.1136/archdischild-2012-302724.0909
VO 97
IS Suppl 2
A1 A Veiga
A1 MCB Soares
A1 R Barbosa
A1 R Taguti
A1 MM Azevedo
A1 CC Mouco
A1 EQ Veiga
A1 NV Moliterno
A1 FM Moliterno
YR 2012
UL http://adc.bmj.com/content/97/Suppl_2/A260.3.abstract
AB Background and Aims Toxoplasmosis is a cosmopolitan infection caused by Toxoplasma gondii, clinical features varying from asymptomatic infection to severe systemic manifestations. Brazil has one of the highest incidence rates of congenital toxoplasmosis in the world with estimated rates of 1:3000 live births. Knowledge of the incidence, etiology, pathogenesis, diagnosis and management of infections during pregnancy, childbirth and neonatal period is relevant because it may cause damage to the fetus and newborn, representing a public health problem worldwide. The aim of this study is evaluate the quality of neonatal screening for congenital toxoplasmosis. Methods Retrospective study based on data collected from the medical records of 39 newborns Alcides Carneiro Hospital (HAC) in Petropolis, Rio de Janeiro, Brazil, from July 2010 to February 2012 whose mothers had seroconversion for toxoplasmosis during pregnancy. We analyzed maternal serology and treatment and clinical manifestations, laboratory and radiological newborn. Results Forty percent of pregnant women under which seroconverted in the 3rd trimester of pregnancy, 33% at 2 and 13% in first trimester. Underwent treatment 35%, 15% and 0% respectively. There were no clinical manifestations of congenital toxoplasmosis, all showed negative IgM and IgG positive 62%. In imaging tests, 5% had changed transfontanel ultrasound (49% unknown), 1% fundoscopy losses (51% ignored), and skull radiography unchanged (23% ignored). Conclusion Given the survey data, we conclude that there was poor adherence to native implementation of adequate prenatal care, underestimation of suspected cases with disabilities in serological screening, limited availability of laboratory diagnostic capabilities and imaging.