TY - JOUR T1 - Epigenetics and child health: basic principles JF - Archives of Disease in Childhood JO - Arch Dis Child SP - 863 LP - 869 DO - 10.1136/adc.2009.165712 VL - 96 IS - 9 AU - A Groom AU - H R Elliott AU - N D Embleton AU - C L Relton Y1 - 2011/09/01 UR - http://adc.bmj.com/content/96/9/863.abstract N2 - Epigenetic mechanisms are believed to play an important role in disease, development and ageing with early life representing a window of particular epigenomic plasticity. The knowledge upon which these claims are based is beginning to expand. This review summarises evidence pointing to the determinants of epigenetic patterns, their juxtaposition at the interface of the environment, their influence on gene function and the relevance of this information to child health. ER -