RT Journal Article
SR Electronic
T1 Epigenetics and child health: basic principles
JF Archives of Disease in Childhood
JO Arch Dis Child
FD BMJ Publishing Group Ltd and Royal College of Paediatrics and Child Health
SP 863
OP 869
DO 10.1136/adc.2009.165712
VO 96
IS 9
A1 A Groom
A1 H R Elliott
A1 N D Embleton
A1 C L Relton
YR 2011
UL http://adc.bmj.com/content/96/9/863.abstract
AB Epigenetic mechanisms are believed to play an important role in disease, development and ageing with early life representing a window of particular epigenomic plasticity. The knowledge upon which these claims are based is beginning to expand. This review summarises evidence pointing to the determinants of epigenetic patterns, their juxtaposition at the interface of the environment, their influence on gene function and the relevance of this information to child health.