TY - JOUR T1 - Subclinical hypothyroidism in childhood JF - Archives of Disease in Childhood JO - Arch Dis Child SP - 280 LP - 284 DO - 10.1136/adc.2009.181800 VL - 96 IS - 3 AU - MJ O'Grady AU - D Cody Y1 - 2011/03/01 UR - http://adc.bmj.com/content/96/3/280.abstract N2 - Subclinical hypothyroidism (SH) is defined as an elevated thyroid stimulating hormone (TSH) in association with a normal total or free thyroxine (T4) or triiodothyronine (T3). It is frequently encountered in both neonatology and general paediatric practice; however, its clinical significance is widely debated. Currently there is no broad consensus on the investigation and treatment of these patients; specifically who to treat and what cut-off level of TSH should be used. This paper reviews the available evidence regarding investigation, treatments and outcomes reported for childhood SH. ER -