PT  - JOURNAL ARTICLE
AU  - MJ O'Grady
AU  - D Cody
TI  - Subclinical hypothyroidism in childhood
AID  - 10.1136/adc.2009.181800
DP  - 2011 Mar 01
TA  - Archives of Disease in Childhood
PG  - 280--284
VI  - 96
IP  - 3
4099  - http://adc.bmj.com/content/96/3/280.short
4100  - http://adc.bmj.com/content/96/3/280.full
SO  - Arch Dis Child2011 Mar 01; 96
AB  - Subclinical hypothyroidism (SH) is defined as an elevated thyroid stimulating hormone (TSH) in association with a normal total or free thyroxine (T4) or triiodothyronine (T3). It is frequently encountered in both neonatology and general paediatric practice; however, its clinical significance is widely debated. Currently there is no broad consensus on the investigation and treatment of these patients; specifically who to treat and what cut-off level of TSH should be used. This paper reviews the available evidence regarding investigation, treatments and outcomes reported for childhood SH.