RT Journal Article SR Electronic T1 Update on the causes, investigation and management of empyema in childhood JF Archives of Disease in Childhood JO Arch Dis Child FD BMJ Publishing Group Ltd and Royal College of Paediatrics and Child Health SP 482 OP 488 DO 10.1136/adc.2009.165357 VO 96 IS 5 A1 Woolf Walker A1 Robert Wheeler A1 Julian Legg YR 2011 UL http://adc.bmj.com/content/96/5/482.abstract AB Despite being recognised for over two millennia and having an increasing incidence in many countries, the management of childhood empyema remains controversial. This review examines the recent literature on its causes and investigation then focuses on its treatment. Following a trial of appropriate intravenous antibiotics, the evidence would currently support the use of chest drain insertion with urokinase instillation as first line treatment with video-assisted thoracoscopic surgery to be used for failure of medical management. A treatment algorithm is proposed to guide clinical practice.