RT Journal Article SR Electronic T1 Infant feeding in the second 6 months of life related to iron status: an observational study JF Archives of Disease in Childhood JO Arch Dis Child FD BMJ Publishing Group Ltd and Royal College of Paediatrics and Child Health SP 850 OP 854 DO 10.1136/adc.2006.114074 VO 92 IS 10 A1 Hopkins, David A1 Emmett, Pauline A1 Steer, Colin A1 Rogers, Imogen A1 Noble, Sian A1 Emond, Alan YR 2007 UL http://adc.bmj.com/content/92/10/850.abstract AB Objective: To investigate the relationship between iron status in infancy and type of milk and weaning solids consumed.Design: An observational cohort study.Setting: 928 term infants from the Avon Longitudinal Study of Parents and Children in 1993–94.Methods: Haemoglobin and ferritin concentrations at 8 and 12 months were assessed in relation to type and quantity of milk intake at 8 months.Results: By WHO criteria, 22.7% of the infants were anaemic at 8 months and 18.1% at 12 months. More breast- than formula-fed infants were anaemic at 8 and 12 months. Cows’ milk as the main drink was associated with increased anaemia at 12 months and low ferritin at 8 and 12 months. No association was found between any nutrients and haemoglobin concentrations. Protein and non-haem iron intakes were positively associated with ferritin concentrations and calcium intake negatively. This effect was more marked in infants being fed cows’ milk. More than 25% of infants in the breast milk and cows’ milk groups and 41% of infants having >6 breast feeds per day had iron intakes below the lower reference nutrient intake. Feeding cows’ milk or formula above 600 ml or >6 breast feeds per day was associated with lower intakes of solids.Conclusions: Both breast and cows’ milk feeding were associated with higher levels of anaemia. Satisfactory iron intake from solids in later infancy is more likely if formula intake is <600 ml per day and breast feeds are limited to <6 feeds per day. Cows’ milk should be strongly discouraged as a main drink before 12 months.