TY - JOUR T1 - Radiological findings in cyclical administration of intravenous pamidronate in children with osteoporosis JF - Archives of Disease in Childhood JO - Arch Dis Child SP - 1087 LP - 1087 DO - 10.1136/adc.2007.129692 VL - 92 IS - 12 AU - C Onwuneme AU - K Abdalla AU - N Cassidy AU - O Hensey AU - S Ryan Y1 - 2007/12/01 UR - http://adc.bmj.com/content/92/12/1087.abstract N2 - A 5-year-old boy with moderately severe osteogenesis imperfecta and spontaneous fractures was treated with serial courses of intravenous pamidronate. Pamidronate is a second-generation bisphosphonate drug that binds strongly to bone mineral and interferes with bone remodelling by slowing osteoclastic bone resorption. It is used in a cyclic dosage … ER -