TY - JOUR T1 - Dapsone therapy for Henoch-Schönlein purpura: a case series JF - Archives of Disease in Childhood JO - Arch Dis Child SP - 985 LP - 986 DO - 10.1136/adc.2004.061598 VL - 90 IS - 9 AU - H Iqbal AU - A Evans Y1 - 2005/09/01 UR - http://adc.bmj.com/content/90/9/985.2.abstract N2 - Henoch-Schönlein purpura (HSP), first recognised by Heberden in 1801, is a systemic, IgA mediated vasculitis of small vessels that is usually self-limiting but may progress to gastrointestinal bleeding, intussusception, and nephropathy. A third of patients will experience recurrences.1 Currently treatment is confined to rest, analgesia, and steroids for refractory abdominal pain,2 and immunosuppressants for complications, especially renal disease. Original reports, predominantly in adults, show that the symptoms of purpuric rash, abdominal pain, and arthritis in HSP respond to treatment with dapsone.3–, … ER -