TY - JOUR T1 - Partially hydrolysed guar gum supplemented comminuted chicken diet in persistent diarrhoea: a randomised controlled trial JF - Archives of Disease in Childhood JO - Arch Dis Child SP - 195 LP - 199 DO - 10.1136/adc.2003.040089 VL - 90 IS - 2 AU - N H Alam AU - R Meier AU - S A Sarker AU - P K Bardhan AU - H Schneider AU - N Gyr Y1 - 2005/02/01 UR - http://adc.bmj.com/content/90/2/195.abstract N2 - Background: Partially hydrolysed guar gum (Benefiber) added to a diet is fermented in the colon, producing short chain fatty acids, which improve intestinal function, including colonic salt and water absorption.Aims: To evaluate the effect of Benefiber supplemented comminuted chicken diet in the treatment of persistent diarrhoea.Methods: One hundred and sixteen children (aged 5–24 months), presenting to Dhaka Hospital with a history of watery diarrhoea for more than 14 days (persistent diarrhoea), were randomised to receive either: (1) comminuted chicken diet with Benefiber (study diet); or (2) comminuted chicken diet without Benefiber (control diet). The study period was seven days.Results: Of 116 children, 57 received the study diet and 59 received the control diet. Diarrhoea resolved in a greater number of children with the study than with the control diet (46/55 (84%) v 36/58 (62%); odds ratio 3.12, 95% CI 1.19 to 8.4). Survival analysis for the duration of diarrhoea also showed a reduced duration of diarrhoea in children receiving the study diet. There was also a trend in daily stool reduction in children receiving the study diet, significant on days 4–7.Conclusion: Results show that Benefiber supplemented comminuted chicken diet enhances recovery of children with persistent diarrhoea, indicating its therapeutic potential. ER -