RT Journal Article SR Electronic T1 American fresh frozen plasma for neonates and children JF Archives of Disease in Childhood JO Arch Dis Child FD BMJ Publishing Group Ltd and Royal College of Paediatrics and Child Health SP 89 OP 91 DO 10.1136/adc.2003.048264 VO 90 IS 1 A1 D R Norfolk A1 A Glaser A1 S Kinsey YR 2005 UL http://adc.bmj.com/content/90/1/89.abstract AB From the spring of 2004 the United Kingdom Blood Services have been importing fresh frozen plasma from United States donors for all neonates and children born after 1 January 1996. The decision to mandate the use of American plasma in this age group was taken by the Department of Health in 2002 as part of its precautionary approach to the risk of transfusion transmitted variant Creutzfeldt-Jakob disease. In this article we explain the background to this decision and explore some of the implications it raises for clinical practice.