RT Journal Article
SR Electronic
T1 Successful radioiodine treatment in a 3 year old child with Graves’ disease following antithyroid medication induced neutropenia
JF Archives of Disease in Childhood
JO Arch Dis Child
FD BMJ Publishing Group Ltd and Royal College of Paediatrics and Child Health
SP 158
OP 159
DO 10.1136/adc.88.2.158
VO 88
IS 2
A1 M A S Rahman
A1 G Birrell
A1 H Stewart
A1 H Lucraft
A1 T D Cheetham
YR 2003
UL http://adc.bmj.com/content/88/2/158.abstract
AB A 3 year old child with Graves’ disease and mitral valve prolapse became neutropenic on carbimazole therapy. She was switched to propylthiouracil but the neutropenia recurred. She was treated with radioiodine but required two doses of 113 MBq and then 198 MBq five months later before becoming hypothyroid. The mitral valve prolapse resolved when she was euthyroid on thyroxine replacement. Antithyroid drugs, surgery, and radioiodine all have a place in the management of the thyrotoxic child.