RT Journal Article
SR Electronic
T1 Hypothyroidism mimicking chronic renal failure in reflux nephropathy
JF Archives of Disease in Childhood
JO Arch Dis Child
FD BMJ Publishing Group Ltd and Royal College of Paediatrics and Child Health
SP 251
OP 252
DO 10.1136/adc.83.3.251
VO 83
IS 3
A1 Martin Bald
A1 Berthold P Hauffa
A1 Anne-Margret Wingen
YR 2000
UL http://adc.bmj.com/content/83/3/251.abstract
AB An adolescent with a history of pyelonephritis and renal scarring had antireflux surgery at the age of 2.5 years. His serum creatinine was high at the age of 14 years (133 μmol/l; glomerular filtration rate (GFR) 56 ml/min × 1.73 m2), and reflux nephropathy with chronic renal failure was diagnosed. Because of a fall in height velocity, endocrinological investigations were performed six months later which showed hypothyroidism caused by autoimmune thyroiditis. Substitution with thyroxine was started; renal function improved to normal six months later (GFR 108 ml/min × 1.73 m2). Metabolic changes of hypothyroidism led to a reduction of GFR in this patient and mimicked chronic renal failure.