RT Journal Article SR Electronic T1 Influence of infant feeding and gluten intake on coeliac disease JF Archives of Disease in Childhood JO Arch Dis Child FD BMJ Publishing Group Ltd and Royal College of Paediatrics and Child Health SP 113 OP 117 DO 10.1136/adc.76.2.113 VO 76 IS 2 A1 H Ascher A1 I Krantz A1 L Rydberg A1 P Nordin A1 B Kristiansson YR 1997 UL http://adc.bmj.com/content/76/2/113.abstract AB OBJECTIVES To study the impact of infant feeding habits and actual gluten intake on gluten induced enteropathy. METHODS A case-referent design, controlling for the HLA alleles conferring increased genetic risk, was used. All 164 siblings of 97 probands were investigated. Eighty five of the siblings, carrying the genes DQA1*0501-DQB1*02 conferring susceptibility for the disease, were investigated by interview, food recording, and taking a small intestinal biopsy sample. Eight cases of silent coeliac disease were found and these were compared with the 73 siblings in whom the diagnosis was excluded. RESULTS No statistically significant differences were found between cases and referents in terms of duration of breast feeding, age at introduction of cows’ milk products, frequency of breast feeding after gluten introduction, and gluten consumption. CONCLUSIONS The studied factors may be of less importance for the development of gluten induced enteropathy.