PT  - JOURNAL ARTICLE
AU  - K Y Lai
AU  - D Skuse
AU  - R Stanhope
AU  - P Hindmarsh
TI  - Cognitive abilities associated with the Silver-Russell syndrome.
AID  - 10.1136/adc.71.6.490
DP  - 1994 Dec 01
TA  - Archives of Disease in Childhood
PG  - 490--496
VI  - 71
IP  - 6
4099  - http://adc.bmj.com/content/71/6/490.short
4100  - http://adc.bmj.com/content/71/6/490.full
SO  - Arch Dis Child1994 Dec 01; 71
AB  - There is no consensus opinion on whether or not cognitive impairments are found in the Silver-Russell syndrome. An investigation of a substantial sample was undertaken, using standardised assessments, in 20 boys and five girls aged 6.0 years to 11.8 years. Mean (SD) birth weights were -2.65 (0.95) SD scores, corrected for gestation. At evaluation the children had a mean (SD) age of 8.8 (1.8) years and a mean height of -2.26 (1.5) SD scores. Tests of cognitive abilities included assessments of general intelligence, reading and arithmetic attainments, and a cognitive processing task. Most had some degree of developmental delay: mean (SD) full scale IQ was 86 (24); 32% scored within the learning disability range (that is, IQ < 70); 40% were reading at least 24 months below their chronological age. Current head circumference correlated highly with full scale IQ. Assessments of special educational needs had been completed on 36%; 48% were receiving speech therapy. Approximately half of children with the Silver-Russell syndrome have significant impairment of their cognitive abilities.