PT - JOURNAL ARTICLE AU - R Hume AU - A Burchell TI - Abnormal expression of glucose-6-phosphatase in preterm infants. AID - 10.1136/adc.68.2.202 DP - 1993 Feb 01 TA - Archives of Disease in Childhood PG - 202--204 VI - 68 IP - 2 4099 - http://adc.bmj.com/content/68/2/202.short 4100 - http://adc.bmj.com/content/68/2/202.full SO - Arch Dis Child1993 Feb 01; 68 AB - The hepatic microsomal glucose-6-phosphatase enzyme was studied in liver samples from 76 premature infants including 15 victims of sudden infant death syndrome. The data obtained were compared with glucose-6-phosphatase activity in liver samples from 95 term infants. In the majority of preterm infants up to 350 days of age the activity of the glucose-6-phosphatase enzyme was at or below the extreme low limit of the normal range in term infants. The premature infants with the lowest hepatic microsomal glucose-6-phosphatase activities are likely to be at risk of hypoglycaemic episodes during periods of relative starvation or stress.