PT - JOURNAL ARTICLE AU - S Jóźwiak AU - M Pedich AU - P Rajszys AU - R Michalowicz TI - Incidence of hepatic hamartomas in tuberous sclerosis. AID - 10.1136/adc.67.11.1363 DP - 1992 Nov 01 TA - Archives of Disease in Childhood PG - 1363--1365 VI - 67 IP - 11 4099 - http://adc.bmj.com/content/67/11/1363.short 4100 - http://adc.bmj.com/content/67/11/1363.full SO - Arch Dis Child1992 Nov 01; 67 AB - Hepatic hamartomas were thought to be a rare finding in patients with tuberous sclerosis. The purpose of this study was to assess their incidence in children with tuberous sclerosis and to review the literature. During 1984-90 we examined 51 children by ultrasonography; there were 25 boys and 26 girls. Their age ranged from 3 months to 18 years. Liver hamartomas were seen in 12 (23.5%) of the children, more often in girls than boys (5:1). Their incidence increased with age reaching 45% in children over the age of 10. They did not produce any symptoms of hepatic dysfunction. Our study and review of reported cases prove that hepatic hamartomas are a common finding in patients with tuberous sclerosis and may be very helpful in providing a more accurate diagnosis and consequently help in genetic counselling.