PT  - JOURNAL ARTICLE
AU  - G Tudor-Williams
AU  - J Frankland
AU  - D Isaacs
AU  - R T Mayon-White
AU  - J A MacFarlane
AU  - M P Slack
AU  - E Anderson
AU  - D G Rees
AU  - E R Moxon
TI  - Haemophilus influenzae type b disease in the Oxford region.
AID  - 10.1136/adc.64.4.517
DP  - 1989 Apr 01
TA  - Archives of Disease in Childhood
PG  - 517--519
VI  - 64
IP  - 4
4099  - http://adc.bmj.com/content/64/4/517.short
4100  - http://adc.bmj.com/content/64/4/517.full
SO  - Arch Dis Child1989 Apr 01; 64
AB  - A prospective survey of children in the Oxford region identified 200 cases of systemic Haemophilus influenzae type b disease in the first three and a half years of the study. The annual incidence in children less than 5 years of age was 33.4/100,000. This represents a cumulative incidence of one systemic infection in 600 children before their 5th birthday. The mortality was 5.0%. The risk of H influenzae type b meningitis was one in 850 with a mortality of 5.6%, and substantial morbidity among survivors. From the total live birth rate, about 1300 cases of systemic H influenzae type b disease, over 900 cases of H influenzae type b meningitis, and 65 deaths would be predicted annually in children in the United Kingdom.