RT Journal Article
SR Electronic
T1 Chromosome abnormalities in pupils attending ESN/M schools.
JF Archives of Disease in Childhood
JO Arch Dis Child
FD BMJ Publishing Group Ltd and Royal College of Paediatrics and Child Health
SP 223
OP 226
DO 10.1136/adc.61.3.223
VO 61
IS 3
A1 M A Lamont
A1 N R Dennis
A1 M Seabright
YR 1986
UL http://adc.bmj.com/content/61/3/223.abstract
AB One hundred and sixty six children attending educationally subnormal/mild (ESN/M) schools were karyotyped as part of a project investigating the aetiology of mild mental retardation. Nine had significant chromosome abnormalities. Five of six children identified during the survey had no dysmorphic features--47,XXY (two), 48,XXYY, 46,XX 15q-, and 46,XX,t(X;19). One dysmorphic boy had a balanced translocation--46,XY,t(3;15). Three were already known--47,XX+21 (two) and 46,XY, 14q+. We suggest that routine karyotyping of children with mild mental retardation be considered.