RT Journal Article
SR Electronic
T1 The medium chain triglyceride diet and intractable epilepsy.
JF Archives of Disease in Childhood
JO Arch Dis Child
FD BMJ Publishing Group Ltd and Royal College of Paediatrics and Child Health
SP 1168
OP 1172
DO 10.1136/adc.61.12.1168
VO 61
IS 12
A1 Sills, M A
A1 Forsythe, W I
A1 Haidukewych, D
A1 MacDonald, A
A1 Robinson, M
YR 1986
UL http://adc.bmj.com/content/61/12/1168.abstract
AB Fifty children with drug resistant epilepsy were treated with the Medium Chain Triglyceride (MCT) Emulsion diet. Eight achieved complete control of seizures (four without anticonvulsant drugs), and with the addition of anticonvulsants four had seizures reduced in frequency by 90% and 10 by 50-90%. The best results were obtained with astatic myoclonic and absence seizures, but control of seizures was improved in four children with tonic-clonic and three with complex partial seizures. Food given at the same time as MCT helped to reduce side effects, and an extra dose of MCT before bedtime improved control of nocturnal seizures.