PT  - JOURNAL ARTICLE
AU  - A R Gatrad
AU  - A P Read
AU  - G H Watson
TI  - Consanguinity and complex cardiac anomalies with situs ambiguus.
AID  - 10.1136/adc.59.3.242
DP  - 1984 Mar 01
TA  - Archives of Disease in Childhood
PG  - 242--245
VI  - 59
IP  - 3
4099  - http://adc.bmj.com/content/59/3/242.short
4100  - http://adc.bmj.com/content/59/3/242.full
SO  - Arch Dis Child1984 Mar 01; 59
AB  - A survey of British born Asian and English populations of children with congenital cardiac anomalies showed an increased incidence in the Muslim Asian population of complex lesions with visceral heterotaxia. There is a very high incidence of parental consanguinity among Muslim Asian children with complex congenital cardiac anomalies that is even higher than in the general Muslim Asian population of the area studied. The evidence suggests an important recessive genetic component in complex cardiac lesions with visceral heterotaxia, but segregation analysis does not support pure recessive inheritance.