TY - JOUR T1 - Liver damage in a neonate with alpha-1-antitrypsin deficiency due to phenotype PiZ null (Z<sup>-</sup>) JF - Archives of Disease in Childhood JO - Arch Dis Child SP - 311 LP - 313 DO - 10.1136/adc.57.4.311 VL - 57 IS - 4 AU - John Burn AU - David Dunger AU - Brian Lake Y1 - 1982/04/01 UR - http://adc.bmj.com/content/57/4/311.abstract N2 - An infant with neonatal liver damage had α-1-antitrypsin deficiency, having inherited the Z allele from the father and the rare null allele from the mother. This indicates that while a lack of serum antiprotease predisposes to early liver disease, homozygosity for the Z allele is not essential. ER -