TY - JOUR T1 - Hypertension and segmental renal hypoplasia causing a syndrome of haemolysis and uraemia. JF - Archives of Disease in Childhood JO - Arch Dis Child SP - 403 LP - 404 DO - 10.1136/adc.56.5.403 VL - 56 IS - 5 AU - R Dumas AU - P Baldet AU - B Rolin AU - R Jean Y1 - 1981/05/01 UR - http://adc.bmj.com/content/56/5/403.abstract N2 - An 11-year-old girl presented with acute renal failure and severe hypertension. The blood film showed thrombocytopenia, numerous fragmented red blood cells, and a reticulocyte count of 10%. An intravenous pyelogram showed a small contracted left kidney, and plasma renin activity was increased in the left renal vein. Treatment with minoxidil and propranolol controlled the hypertension. After nephrectomy the hypertension resolved. Light microscopical examination of the left kidney showed a segmental renal hypoplasia. Malignant arterial hypertension can provoke a syndrome of haemolysis and uraemia in children. Aggressive lowering of blood pressure leads to an improvement in renal function. ER -