TY - JOUR T1 - Exercise-induced bronchocontriction, skin sensitivity, and serum IgE in children with eczema. JF - Archives of Disease in Childhood JO - Arch Dis Child SP - 912 LP - 917 DO - 10.1136/adc.51.12.912 VL - 51 IS - 12 AU - J F Price AU - J J Cogswell AU - M C Joseph AU - G M Cochrane Y1 - 1976/12/01 UR - http://adc.bmj.com/content/51/12/912.abstract N2 - Forty-two children with eczema were studied for exercise-induced astham (EIA), skin sensitivity to prick testing, blood eosinophil count, and immunoglobulins. 29 had a fall in peak expiratory flow rate after exercise greater than 20% and of these, 23 had symptoms of wheezing. 13 of the eczematous children showed a fall of less than 20%. The children with EIA showed greater cutaneous sensitivity (p less than 0.001) and a higher total serum IgE (p less than 0.025). 3 of the group with a fall of less than 20% had allergic rhinitis with skin sensitivity to grass pollen. The remaining 10 had no clinical evidence of allergic disease, other than eczema and skin sensitivity, and total IgE fell within the normal range. It is suggested that in a proportion of chilren with eczema there is little evidence of reaginic allergy. ER -