RT Journal Article
SR Electronic
T1 Wilm's tumour, hypospadias, and cryptorchidism in twins.
JF Archives of Disease in Childhood
JO Arch Dis Child
FD BMJ Publishing Group Ltd and Royal College of Paediatrics and Child Health
SP 243
OP 245
DO 10.1136/adc.52.3.243
VO 52
IS 3
A1 J V Bond
YR 1977
UL http://adc.bmj.com/content/52/3/243.abstract
AB Twin boys, both of whom had hypospadias and bilateral cryptorchidism, each developed a left-sided Wilms's tumour. The first twin was found to have an advanced multifocal tumour at the age of 15 months and died with local recurrence and pulmonary metastases. The diagnosis was made in the second twin one month later and at nephrectomy the tumour was found to be encapsulated without metastases; he is disease-free 12-years later. Although the histological appearances were similar in each twin, the tumours did not develop at the same rate and did not show the 'mirror-image' pattern suggested for embryonal tumours in identical twins.