PT  - JOURNAL ARTICLE
AU  - J V Bond
TI  - Wilm's tumour, hypospadias, and cryptorchidism in twins.
AID  - 10.1136/adc.52.3.243
DP  - 1977 Mar 01
TA  - Archives of Disease in Childhood
PG  - 243--245
VI  - 52
IP  - 3
4099  - http://adc.bmj.com/content/52/3/243.short
4100  - http://adc.bmj.com/content/52/3/243.full
SO  - Arch Dis Child1977 Mar 01; 52
AB  - Twin boys, both of whom had hypospadias and bilateral cryptorchidism, each developed a left-sided Wilms's tumour. The first twin was found to have an advanced multifocal tumour at the age of 15 months and died with local recurrence and pulmonary metastases. The diagnosis was made in the second twin one month later and at nephrectomy the tumour was found to be encapsulated without metastases; he is disease-free 12-years later. Although the histological appearances were similar in each twin, the tumours did not develop at the same rate and did not show the 'mirror-image' pattern suggested for embryonal tumours in identical twins.