PT  - JOURNAL ARTICLE
AU  - S C Comay
AU  - C D Karabus
TI  - Peripheral gangrene in hypernatraemic dehydration of infancy.
AID  - 10.1136/adc.50.8.616
DP  - 1975 Aug 01
TA  - Archives of Disease in Childhood
PG  - 616--619
VI  - 50
IP  - 8
4099  - http://adc.bmj.com/content/50/8/616.short
4100  - http://adc.bmj.com/content/50/8/616.full
SO  - Arch Dis Child1975 Aug 01; 50
AB  - Gangrene of the extremities complicating diarrhoea and severe hypernatraemic dehydration occurred in 6 infants. This is a rare complication of gastroenteritis, and its association with hypernatraemia does not seem to have previously been emphasized. The increased blood viscosity resulting from serum hyperosmolarity may have been responsible for the gangrene, and studies in our patients suggested that disseminated intravascular coagulation was present. In addition to fluid and electrolyte replacement, the infants were treated with heparin with some recovery of the affected extremities.