RT Journal Article
SR Electronic
T1 Prognostic significance of radiological bone involvement in childhood acute lymphoblastic leukaemia.
JF Archives of Disease in Childhood
JO Arch Dis Child
FD BMJ Publishing Group Ltd and Royal College of Paediatrics and Child Health
SP 530
OP 533
DO 10.1136/adc.52.7.530
VO 52
IS 7
A1 Masera, G
A1 Carnelli, V
A1 Ferrari, M
A1 Recchia, M
A1 Bellini, F
YR 1977
UL http://adc.bmj.com/content/52/7/530.abstract
AB In 98 children with acute lymphoblastic leukaemia, aged 1 to 12 years, the prognostic significance of radiological bone involvement was studied. The mean duration of remission and of survival was much shorter in cases with multiple bone involvement (3 or more bones) than in those where bone involvement was absent. In those cases presenting with 1 or 2 bone lesions no statement of prognostic significance can be made at this stage. A radiological skeletal survey should be made in all children presenting with leukaemia to identify those (about 15%) having multiple bone lesions and therefore a poor prognosis, in order that they can be given more intensive therapy.