PT  - JOURNAL ARTICLE
AU  - K. M. Goel
AU  - R. A. Shanks
TI  - Scleroderma in childhood
AID  - 10.1136/adc.49.11.861
DP  - 1974 Nov 01
TA  - Archives of Disease in Childhood
PG  - 861--866
VI  - 49
IP  - 11
4099  - http://adc.bmj.com/content/49/11/861.short
4100  - http://adc.bmj.com/content/49/11/861.full
SO  - Arch Dis Child1974 Nov 01; 49
AB  - Five cases of scleroderma in childhood have been reviewed. All presented with cutaneous complaints. Raynaud's phenomenon occurred in 2 and Sjögren's syndrome in one. A patient with linear scleroderma and hemiatrophy developed subcutaneous calcification 5 years after the onset of disease. Of the 5 patients reviewed, 2 have been clinically well for several years, while the disease is progressive in the remaining 3. Because of the clinical and serological overlap, confusion is possible between dermatomyositis, scleroderma, juvenile rheumatoid arthritis, and systemic lupus erythematosus, particularly when these connective tissue disorders are so uncommon in children. It appears that scleroderma in children may be less severe than in adults and that systemic involvement is less common. The presence of Raynaud's phenomenon, antinuclear factor, lupus erythematosus (LE) cells, and a raised erythrocyte sedimentation rate indicate a poor prognosis.