TY - JOUR T1 - Renal loss of folate in the newborn infant JF - Archives of Disease in Childhood JO - Arch Dis Child SP - 292 LP - 296 DO - 10.1136/adc.49.4.292 VL - 49 IS - 4 AU - M. J. Landon AU - E. N. Hey Y1 - 1974/04/01 UR - http://adc.bmj.com/content/49/4/292.abstract N2 - Renal excretion of folate during the first 5 days of life has been measured in 10 infants of 31 to 40 weeks' gestation and compared with inulin clearance. Average daily folate loss per unit surface area (23 μg/m2) was nearly 8 times as high as in adult life and more than enough to account for the observed fall in plasma folate activity. No difference was detected between the pattern of folate excretion in preterm and term infants. Poor tubular reabsorption of filtered folate is thought to be responsible for the loss observed. ER -