RT Journal Article SR Electronic T1 Duodenal bile acids in infancy. JF Archives of Disease in Childhood JO Arch Dis Child FD BMJ Publishing Group Ltd and Royal College of Paediatrics and Child Health SP 837 OP 843 DO 10.1136/adc.50.11.837 VO 50 IS 11 A1 D N Challacombe A1 S Edkins A1 G A Brown YR 1975 UL http://adc.bmj.com/content/50/11/837.abstract AB Duodenal bile acids have been estimated in three age groups in infancy from birth to 7 months, and age-related changes have been shown. The lowest concentrations of duodenal bile acids occurred in the youngest infants, and increasing concentrations were found with increasing age. Taurine conjugated bile acids predominated in early infancy, while in older infants bile acids were mainly conjugated with glycine. The probable presence of taurolithocholic acid in the duodenal bil of 2 newborns before the establishment of a gastrointestinal microflora remains to be confirmed, but could result either from transplacental passage of secondary bile acids or from endogenous synthesis by the fetal liver.