RT Journal Article
SR Electronic
T1 Haemangioma with coagulopathy: sustained response to prednisone.
JF Archives of Disease in Childhood
JO Arch Dis Child
FD BMJ Publishing Group Ltd and Royal College of Paediatrics and Child Health
SP 809
OP 812
DO 10.1136/adc.50.10.809
VO 50
IS 10
A1 J Evans
A1 A D Batchelor
A1 G Stark
A1 W S Uttley
YR 1975
UL http://adc.bmj.com/content/50/10/809.abstract
AB Two cases of giant haemangioma with thrombocytopenia are described. A satisfactory and sustained response to prednisone was achieved in respect of both coagulation abnormalities and tumour size. It is proposed that prednisone is effective by enhancement of thrombosis and reduction of fibrinolysis within the tumour, thus promoting a natural form of resolution. It is suggested that prednisone therapy should be first-choice treatment of complicated haemangiomas.