eLetters

534 e-Letters

published between 2003 and 2006

  • Moderately high doses stilll need to be considered for very young children
    Dominic P Cochran

    Dear Editor

    In relation to the question of adrenal suppression when using higher doses of inhaled corticosteroid, I believe there is an aspect of dose selection which has not been mentioned by previous authors.

    There is limited data on the question of intra-pulmonary drug deposition in children under 3 years but the studies that have been publised seem to indicate that around 1-2% of the drug released int...

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  • Bedsharing, Maternal Smoking, and SIDS
    James J. McKenna

    Dear Editor

    Re: James et al.[1] This article makes an important step forward by indicating by its title that--the subset of bedsharing mothers studied were very different from many others--who, for example, do not smoke, or who, might, unlike your mothers, not smoke AND breast feed.

    However, I had one disappointment with this otherwise important paper. The authors state in their conclusions...

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  • Use of inhaled corticoseroids in children
    Mike Devoy

    Dear Editor

    I read with interest the article Survey of adrenal crisis associated with inhaled corticosteroids in the United Kingdom by Todd et al. and the accompanying editorial in the December issue of Archives of Disease in Childhood.

    In the reported cases, the children had been administered substantially (up to 5 times) higher than the Glaxo SmithKline Core Data Sheet recommended Flixotide d...

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  • Infant sleep study - validity not clear?
    Phyll Buchanan

    Dear Editor

    For many new parents, their baby sleeping through the night is an important milestone, so I read this study with some interest. However I was puzzled to see the background characteristics listed in table 1 belonged to the overall group of mothers and infants (as previously reported)[1] and not to the subgroup of babies reported in this study – those babies who were deemed to be ‘at-risk’ with a high...

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  • Treatment adherence: surely not in the role of the school teacher?
    Marie A Wheeler

    Dear Editor

    Whilst agreeing with the fact there is ample proof regarding poor compliance with inhaled corticosteroid (ICS) administration in children with asthma,I feel uneasy regarding the suggestion of a role for teachers at school in carrying the responsibility of administration.

    Whilst it is common practice for schools( usually primary) to administer beta-2 agonists on a regular or p.r.n basis, u...

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  • The Famous Five
    Ian D Wacogne

    Dear Editor

    Eagle-eyed readers who know their Enid Blyton will have immediately spotted an error. Fatty wasn't a member of the Famous Five, but a member of the Five Find-Outers.

    I corrected this when the postcard was first proof-read and my original Five Find-Outers was changed to Famous Five. However, the Famous Five are much more, er, Famous and the Five Find-Outers scans so badly that it must have just...

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  • About atropine in IHPS
    Santhosh Rajagopal

    Dear Editor

    The ongoing discussion regarding medical management of Infantile Hypertrophic Pyloric Stenosis made interesting reading. I would like to point out that an Indian study has been published in Indian Pediatrics of October 2001. This study involved 52 infants and had a 92 percent success rate. I quote the Results part of the study verbatim:

    "Medical treatment of IHPS with atropine was successful in...

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  • Adrenal crisis due to inhaled steroids not underestimated
    Geoffrey RG Todd

    Dear Editor

    In response to comments by Pearce and Mabin on Professor Russell’s editorial[1] on our paper.[2]

    They doubt that our survey underestimated the true scale of the problem. I can inform them that this is not the case. Since our survey was completed we have been notified of a further 7 cases (5 children, 2 adults). All but one of the children had been taking fluticasone in similar dosages...

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  • Role of leptin in infection and autoimmunity
    G.N. Malavige

    Dear Editor

    Leptin is a cytokine involved in the regulation and generation of immune responses, particularly T cell responses. It is an adiposite-derived hormone structurally similar to IL-2,[1] which mainly acts as a T cell growth factor. Furthermore, it also regulates cytokine production, activates macrophages[3] and has an important role in angiogenesis and wound healing.[3] Concentrations of leptin increase durin...

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  • Improving mental health through parenting programmes: are the results valid?
    Dr Srinivas S Gada

    Dear Editor

    We read the above article with interest.

    First, the percentage of questionnaires returned from the survey should have been 61.8% not 70%, as reported.

    Second, mental health problems are prevalent in people of lower socioeconomic class. Unfortunately, parents from manual class were seriously underrepresented in the above study.[1] The results from educated predominantly caucasian people fro...

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