eLetters

492 e-Letters

published between 2005 and 2008

  • History of Children's Hospitals - a growth area?
    Oliver R Dearlove

    Dear Editor,

    Dr Goldboom has written an interesting piece on the evolution of children’s hospitals which deserves comment. He mentions Dickens’ support for Great Ormond Street in Our Mutual Friend in 1865. There is certainly a change on the deaths of Paul Dombey – tuberculosis and at home,(1848) and Little Nell, (1840) in the old Curiosity Shop of which Oscar Wilde wrote: “one must have a heart of stone to read t...

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  • congenital hypothyroidism:no adverse effects of high dose thyroxine treatment on adult memory, atten
    oscar, m jolobe

    Dear Editor,

    Thank you for publishing my letter on line. I wish to point out that I made an error in the references:- Reference(2) ought to read as follows:- (2). Mayberry WE., Gharib H., Bilstad JM., Sizemore GW Radioimmunoassay for human thyrotropin. Clinical value in patients with normal and abnormal thyroid function Annals of Internal Medicine 1971:74:471-80

  • congenital hypothyroidism: no adverse effects of high dose thyroxine treatment on adult memory...
    Oscar M Jolobe

    Dear Editor,

    In the above study, serum thyroid hormone(T4) concentrations were utilised as a measure of severity of congenital hypothyroidism(CH), to the exclusion of serum thyroid hormone(TSH) levels [1]. This approach fails to recognise that, notwithstanding an overall inverse correlation between serum T4 and serum TSH concentrations in primary hypothyroidism, there is, nevertheless, a considerable degree of inte...

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  • Between newborn and school hearing screening programmes
    Bolajoko O. Olusanya

    Dear Editor,

    The audit by Fonseca et al [1] underscores the value of school hearing screening programme (SHSP) in child health surveillance in UK and beyond. The degrees of hearing loss mostly prevalent in mainstream schools are slight-to-moderate (16 – 40 dB HL). However, children with hearing loss in this range encounter more difficulties with receptive rather than expressive linguistic communication. The...

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  • Bacterial pneumonia in RSV infections
    I-C. Sam

    Dear Editor,

    Duttweiler et al recently reported that 25/57 (43.9%) of intubated infants admitted with RSV bronchiolitis had concomitant bacterial pneumonia.[1] Diagnosis was made on a microbiological basis of significant bacterial growth and leucocytes seen in routinely obtained tracheal aspirates, with no other factors (clinical or radiological) taken into account.

    We agree that diagnosing bact...

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  • Hypoglycaemia in LGA neonates
    Floris Groenendaal

    Dear Editor,

    We interpret the findings of the interesting, and accurate study by Brand et al [1] regarding hypoglycaemia in LGA neonates in a different way. As all neonates in their study with hypoglycaemia were treated with either intravenous or oral glucose, and all but 3 neonates received formula feeding in addition to breast milk, one cannot conclude from this study that no treatment is needed and even...

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  • Diagnosis of coeliac disease
    Anthony K. Akobeng

    Dear Editor,

    I read with interest the article by Kwiecen et al [1] on the long- term follow-up of children suspected to have coeliac disease (CD). I was surprised at the apparent over-reliance on serological tests for the diagnosis of CD, and the increased number of small intestinal biopsies that this seems to have led to. Because her initial antiendomyseal antibody tests were negative, ‘patient number...

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  • Informed choice: the importance of values and attitudes of individuals
    Theresa M Marteau

    Dear Editor,

    Olusanya and colleagues, in replying to our letter regarding their paper on informed choice in the context of hearing screening [1], raise the fundamental point regarding whose values should inform patients’ choices. Implicit in this, is whether it is possible for parents to make an informed choice to decline a public health intervention. They assert that it is "immoral to ignore a negative attitud...

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  • What about the cost?
    Mike Farrall

    Dear Editor,

    I'm unable to find any consideration of the cost of atomoxetine in the article. This is unfortunate as the article is positive towards this new drug , but ignores it's significantly increased cost when compared to methylphenidate.

    Locally we feel this should not be a first line drug due to it's cost , unless there are clear contraindications to methylphenidate.

  • Prudent?
    Adrian H Sie

    Dear Editor,

    I am concerned that the conclusion arrived at by the authors that "it seems prudent to investigate... by means of a micturating cystourethrogram (MCUG)" is unjustified.

    Micturating cystourethrogram is an invasive test involving discomfort, cost and radiation. We must justify its use by evidence that the information it provides is likely to influence management or prognosis.

    The aut...

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