264 e-Letters

published between 2008 and 2011

  • Should food supplementation be our aim to eradicate widespread Vitamin D deficiency in the UK Re: Recent trends and clinical features of childhood Vitamin D deficiency to a childrens hospital in Glasgow."1
    Lisa M Kehler

    We read your article with interest as we have recently been reviewing cases of Vitamin D deficiency diagnosed at Birmingham Childrens Hospital's Emergency Department.

    We reviewed data from the emergency department from March 2009 to March 2010. Over a period of 12 months we identified 89 patients with low vitamin D levels (total Vitamin D level less than 50nmol/litre), with 83% of those having very low Vitamin D...

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  • Does lidocaine spray prevent midazolam induced nasal burning? No
    Burhan Apiliogullari

    Dear Editor, We have read the interesting study by Chiaretti et al.[1] which concluded that intranasal lidocaine spray given prior to intranasal midazolam can eliminate burning or pain in children. The purpose of this letter is to share our experience associated with the use of nazal lidocaine spray in patients both adult and children. Midazolam is used to provide sedation for many years in children [2]. Physicians are...

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  • Do we know the true laboratory value to confirm Vitamin D deficiency in Children?
    Egware B Odeka

    I read with very keen interest the editorial of Davies et al from Southampton and particularly agree with the heading '' Preventable but no strategy: Vitamin D deficiency in the UK'' In 2005(1) I published an observational study from Oldham on the increasing trend in the number of cases of Rickets from the ethnic population. In our study population, from a total of approximately 50,000 children (2001 census) 20.8% are fr...

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  • More work needs to be done to improve primary care prescribing pattern in paediatric asthma
    Sandra Y Chuang

    Elkout et al's study on prescribing practices in primary care concluded that the data 'appeared to reflect growing awareness of and adherence to guideline recommendations'.(1) They based their conclusions on a decreased prescription of high unlicensed doses of inhaled costicosteroid (ICS), and low numbers of long acting beta agonist (LABA) monotherapy. Our interpretation of the data is not as optimistic. The study dem...

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  • Propranolol for infantile hameangiomas: waiting for randomised clinical trials or working at prospective registry?
    Federico Marchetti

    Dear Editor,

    in the conclusions of their excellent review Starkey and Shahidullah [1] suggest that propranolol should be reserved just for severe cases of haemangioma, while for the other children which deserve treatment, the use of propranolol would be the second choice, pending the results of randomised clinical trials (RCTs) comparative to corticosteroids. We do not agree with this conclusion, as it is in con...

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  • Confusion
    Graham C Smith

    I have read with interest this article from Jones et al. I am however slightly confused by the Conclusion. It states that "Indirect evidence leads the authors to recommend the use of atropine during septic and late hypovolaemic shock, when using suxamethonium." This implies atropine should only be used in hypovolaemic states when suxamethonium is being used, while I have read the body of the article to support the conclus...

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  • Reduction of risk of disseminated tuberculosis in young children by BCG immunisation may be caused by a decreased risk of infection.
    Michael Eisenhut

    The author of a review on the potential role of new vaccines in elimination of childhood tuberculosis emphasized that modern trials of a new tuberculosis vaccines pose the challenge of diagnostic endpoints for childhood tuberculosis and immune correlates of vaccine-induced protection (1). The author did not take into account major progress that has recently been achieved in understanding the effect of BCG immunisation....

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  • Response to Lucina, ADC 2011;96:496
    vaskar saha

    Dear Lucina,

    Thank you for reporting on the outcome of our trial in children with relapsed ALL. As you stated in the first sentence the results were better with Mitoxantrone and therefore the survival figures given in the penultimate sentence are wrong - i.e they have been reversed. The last sentence is taken out of context and may mislead readers. The "warrants further investigation" refers to the use of Mitox...

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  • Infant formulas are replete with a known behavioural neurotoxin
    Christopher Exley

    We very recently published a paper in BMC Pediatrics (http://www.biomedcentral.com/1471-2431/10/63) in which we demonstrated that all infant formulae contained very high levels of the known neurotoxin aluminium. It should come as no surprise to anyone in this field that feeding formula milk, which contains an order of magnitude higher concentration of aluminium than breast milk, could be associated with impaired behavio...

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  • Future implications
    Dylan M Wilson

    The authors rightly point out in their introduction that there is evidence (reference 12 Gargiullo P et al N Engl J Med 2007; 356:1121-9) of loss of vaccine-induced immunity over time, and that Australia will likely have to adopt a two-dose varicella schedule, which is not the case currently. I wonder if the authors have any opinion on how this will impact future maternity care in 15-20 years time and whether this will see...

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