140 e-Letters

published between 2015 and 2018

  • Using time and serial measurements to improve diagnostic strategies in febrile children
    Ruud G. Nijman

    Response to: 1 Segal I, Ehrlichman M, Urbach J, Bar-Meir M. Use of time from fever onset improves the diagnostic accuracy of C-reactive protein in identifying bacterial infections. Arch Dis Child. Nov 2014;99(11):974-978.

    We thank Segal et al. for their work and congratulate them with this interesting paper. The diagnostic value of CRP as reported by Segal et al. is very much in line with earlier work, and in ke...

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  • Peanut anaphylaxis diagnosis
    Giorgio Ciprandi

    The peanut allergy (PA) prevalence is about 1-2% in children. PA may account also for severe food allergy, such as anaphylaxis (1). The severity of reactions may depend on the type of allergen component sensitization. In this regard, at least 11 peanut allergen proteins have been identified and characterized. Ara h 1, 2, and 3 are the major peanut allergens and belong to the seed storage proteins family (Ara h 1 is a vi...

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  • Environmental tobacco smoke and effect on children
    Dr Linzi Williamson

    Dr Editor, We read with interest the publication by Feleszko Ruszczynski M, Jaworska J et al on the effect of Environmental tobacco smoke exposure and risk of allergic sensitisation in children.

    As a trainer and my Paediatric ST3 in the North West deanery we write to thank you for the article referenced above. we found it very interesting read indeed and it has really enhanced the understanding of the risks of...

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  • Making the most of measles vaccination
    Andreas Rieckmann

    We thank Bustreo, Okwo-Bele, and Kamara for a comprehensive overview of the impressive achievements by the Global Alliance for Vaccines and Immunization on reducing child mortality world wide by providing vaccines[1]. With regard to measles vaccine, the authors note that child mortality in Niger was almost halved from 1998 to 2009, and measles vaccination contributed to this achievement. They refer to a Lives Saved Tool...

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  • Use of Carbamazepine in the Treatment of Childhood Rolandic Epilepsy
    William Whitehouse

    Authors Maria Moran1, Nikolina Docheva2, William Whitehouse 1,2 1. Nottingham Children's Hospital, 2. University of Nottingham

    We were interested to read the article by Mellish et al.(1) which reports preference for carbamazepine first line for UK paediatricians treating Benign Rolandic Epilepsy (also known as Benign Epilepsy with Centrotemporal Spikes), perhaps better called Childhood Rolandic Epilepsy (CRE), a...

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  • Shape of Training and Integrated Child Health
    Robert E Klaber

    Thank you for your response to our article on Shape of Training, and for sharing your interesting and innovative programme for GP registrars in Northumbria, UK.

    We know of a number of different innovative 'integrated child health' programmes that are emerging across the UK and would encourage clinicians and educators innovating in this area to continue to evaluate programmes and to share learning. Your experienc...

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    Patrick J. Gavin

    To the Editor

    We read with interest the recent report by Murphy and Oshin regarding reptile-associated salmonellois (RAS) in children aged <5 years in South West England [1]. We agree that further work is required to better inform the public of the potential risks pet reptiles pose for infants and young children. Ireland, as elsewhere, has seen an increase in ownership of exotic pets, particulary reptiles, and...

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  • A response to 'Shape of Training: the right people with the right skills in the right place'
    Graeme M. Denman

    We welcome Kalber et al's article on the 'Shape of Training', particularly in relation to the needs of primary care clinicians and wish to share with the authors our experience of innovative primary care training.

    Paediatric rheumatology is an exemplar of a paediatric subspecialty focussed on the management of specific diseases, such as Juvenile Idiopathic Arthritis, by multidisciplinary care. One of the challe...

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  • Developmental influences on the pharmacokinetics and pharmacodynamics of midazolam
    Frans B. Plotz

    I have read with great interest the systematic review to determine the extent of inter-individual variation in clearance of midazolam in children and to establish which factors are responsible for this variation (1). The authors found that the coefficient of clearance in plasma was greater in critically ill patients than non-critically ill patients. Furthermore, there is also a large inter-individual variation in midazola...

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  • Cardioinversion for supraventricular tachycardia
    Paul A.J. Heaton

    There is not much new under the sun, and this includes headstands as a treatment for supraventricular tachycardia (SVT). In 1995 I reported this technique as an effective method of converting SVT to sinus rhythm [1]; details of this safe and simple technique were published widely in the medical press at the time [2]. The manoeuvre had been discovered by the father of a patient in desperation when his son suffered a prolo...

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