163 e-Letters

published between 2011 and 2014

  • International Charter for Ethical Research Involving Children (ERIC) 2013
    Andrew N. Williams

    Professor Modi's excellent review has a curious omission that of the International Charter for Ethical Research Involving Children (ERIC) 2013.

    http://childethics.com/ accessed November 2nd 2014

    Its project partners include, amongst others, the UNICEF Office for Research and Childwatch International Research Network.

    This Charter addresses the issues raised in her review about moving forwa...

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  • Re: Clarifying the diagnosis of PBB
    Francis J Gilchrist

    Authors: Francis J Gilchrist1,2 ,Mark G Pritchard1, Warren Lenney1,2.

    1. Academic Department of Child Health, University Hospital of North Staffordshire, Newcastle Road, Stoke-on-Trent ST4 6QG, United Kingdom

    2. Institute for Science and Technology in Medicine, Keele University, Guy Hilton Research Centre, Thornburrow Road, Stoke-on-Trent ST4 7QB, United Kingdom

    Correspondence Dr Francis J Gil...

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  • Clarifying the diagnosis of PBB
    Anne B Chang

    We congratulate Dr Pritchard and colleagues for reporting on a retrospective follow-up of their patient cohort with protracted bacterial bronchitis (PBB) and thank them for acknowledging the importance of PBB as a cause of chronic cough. The diagnostic criteria of PBB do however need clarification as the 10 children whose wet cough failed to resolve with antibiotics do not have PBB. Instead, they may have bronchiectasis,...

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  • Distinction between bronchopneumonia, acute bronchiolitis, and asthma
    Davendralingam Sinniah

    Acute bronchiolitis and asthma come under the category of obstructive airway disease while bronchopneumonia does not. The main clinical manifestation of an obstructive airway disease would be hyperinflation that would have the clinical features of viscero-ptosis (upper border of liver pushed down), and loss of cardiac dullness on chest percussion.The other clinical feature of obstructive airway disease is prolonged expi...

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  • Management of chronic hepatitis B infection - will NICE guidance lead to over investigation?
    Andrew Riordan

    We were pleased to read Dr Davison's review of the two recently published guidelines for managing chronic Hepatitis B infection in children [1]. We have recently audited our practice against both of these guidelines. As Dr Davison points out; "The level of Alanine transaminase (ALT) at which treatment should be considered highlights a fundamental difference between the guidelines". NICE suggests that ALT in males above 3...

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  • How to make a microbiologist go pale
    Ian Wacogne
    There are a few ways in which we can induce funny turns in our microbiology colleagues. One of the easiest is to say, within their earshot: "We'll stop the antibiotics if the cultures are negative". Blood cultures are a terrible gold standard. If they're positive, for a plausible organism, then they're useful - they allow you to refine antimicrobial therapy, and make decisions about duration etc. But negative cultures? My pr...
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  • Vitamin D supplementation - The North Tyneside Experience
    Stephen Owens

    The Department of Health (DoH) recommends universal vitamin D supplementation for non-formula-dependent children aged 6 months to 5 years [1]. Following the report by Jamieson et al. [2], we share similar data from North Tyneside, showing that few children are being supplemented with vitamin D and that parental awareness of current recommendations is poor.

    We distributed questionnaires to consecutive parents an...

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  • Is litigation an indispensable form of protection against error
    Sze M Ng

    I read with great interest, Dr Rosenbloom's recent article. He discusses how difficult issues are raised involving blame when a medical error is discovered but the process may offer families restitution and compensation. 'Parental responsibility' is a term used to describe the legal duty that a parent has to their child (1). Parents act, therefore, as surrogate decision makers on the basis of what they believe to be in...

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  • Anxiety disorders in children with tics
    Sally J Robinson

    We read with great interest the recent review article by Creswell, Waite and Cooper on 'Assessment and management of anxiety disorders in children and adolescents'. The article brought to the forefront the importance of accurately identifying and treating anxiety disorders during development, with an encouraging discussion of new treatment strategies and delivery approaches to increase access to psychological therapies fo...

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  • Re: Epidemiology of Paediatric Firearm Injuries
    Saranya Srinivasan

    We appreciate the response from Murch(1) and colleagues as it highlights the dramatic difference in firearm injury rates between the United Kingdom and the United States. Great Britain's firearm regulation is among the strictest in the world while there is significant state to state variability in the United States (2, 3). A study by Fleegler (3), et al. demonstrated that greater statewide firearm regulations are asso...

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