326 e-Letters

published between 2007 and 2010

  • Increased mortality in patients managed with electronic prescribing
    Michael Eisenhut

    Dear Editor,

    In a recent review measures to reduce paediatric prescribing errors were discussed (1). The author discussed computerised physican order entry systems (CPOE) as a measure forming part of the NHS electronic prescription service, which is supposed to be extended over the coming years. The author pointed out the reduced prescribing error rate found with this method in previous studies and mentioned minor issue...

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  • Actigraphy and sleep fragmentation
    Harish Rao

    O'Donnell and colleagues, in their study have shown that polysomnography is still the gold standard for detecting sleep fragmentation in children with OSA, despite advances in actigraphy technology.

    The 2002 AASM practice parameters update on role of actigraphy clearly states that actigraphy is not indicated for the routine diagnosis, assessment of severity, or management of any of the sleep disorders [1]....

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  • Limbic Encephalitis is not Rare in Children and Adolescents
    Huei-Shyong Wang

    We read with great interest the article about limbic encephalitis (LE) in children and adolescents by Haberlandt et al.1

    In the analysis of National Hospital Discharge data, the cause of encephalitis was unknown in 60% of cases.2 We have similar experience in children. Recently, we found about half of those unknown childhood encephalitides had positive autoantibodies including anti-amphiphysin antibody that on...

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  • Diagnosis of Ataxia-telangiectasia and molecular defects associated with HIGM syndrome.
    Rittick Patowary

    In response to your article " Ataxia- telangiectasia patients presenting with hyper-IgM syndrome", by Noordzij J G, Wulffraat N M et al, in your esteemed journal, Archives of Disease in Childhood, June 2009, volume 94, Issue 6, we would like to highlight and bring a few points to your attention, namely: 1. Regarding Ataxia-telangiectasia, although the diagnosis is clinically difficult in very young children, it is not ent...

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  • Electronically turning the audit cycle wheel to improve prescribing habits

    Dear Professor Bauchner,

    Re: Electronically turning the audit cycle wheel to improve prescribing habits

    Medication errors in paediatrics are acknowledged as common with up to 13% of prescriptions having errors and administration mistakes occurring in up to 19% of admissions.[1]. Safer prescribing is therefore recognised as an important issue and effective strategies to improve it continue to be requi...

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  • The use of ondansetron for the treatment of vomiting in acute gastroenteritis in children: from evidence to clinical use
    Federico Marchetti


    Howard S (1) in the review on the use of oral ondansetron in children with acute gastroenteritis show that the drug produces a statistically significant reduction in the need for intravenous fluids, admissions to hospital, and amount of vomiting in these children.

    In the clinical practice antiemetic drugs are frequently used in children with gastroenteritis. A recent retrospective survey that ret...

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  • Food as source of outbreaks of group A streptococcal disease
    Michael Eisenhut

    A recent report described an outbreak of scarlet fever in a primary school (1). The outbreak investigation concluded that person to person transmission was the main source of transmission. This does not explain the simultaneous illness in a large number of children (n=29) occurring within 5 days and ongoing transmission over a month despite rigorous exclusion of cases from school. The investigation did not take into acc...

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  • Prolonged jaundice
    David M Hall

    Rodie et al comment on the NICE guidelines for prolonged jaundice in the newborn. Our study in Sheffield (Crofts DJ et al, Acta Paed. 1999; 88: 969-74) highlighted the dilemma created by guidelines devised by specialists for use in the community by primary care staff. Having been alerted to be more than ordinarily vigilant for prolonged jaundice, some staff had difficulty in deciding whether jaundice was present or no...

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  • Empowerment in paediatric clinical trials. Re: Parental Comprehension and Satisfaction in Paediatric Clinical Trials: A Prospective Study on Childhood Leukaemia
    Ceri Evans

    Dear Sir,

    We read with interest the paper "Parental Comprehension and Satisfaction in Paediatric Clinical Trials: A Prospective Study on Childhood Leukaemia" (1). We feel that this raises some important issues.

    Firstly, patient choice is becoming an increasingly important aspect of healthcare and involvement in clinical trials should not be exempt from this. True patient choice can only be realised with...

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  • Effects of dynamic elastomeric fabric orthoses (DEFOs) on children with cerebral palsy.
    Martin J Watson

    I read with interest the article 'Do lycra garments improve function and movement in children with cerebral palsy?' (ADC 2010 95(5): 393-395). I encountered this paper as we are currently involved in completing a systematic review on this topic, and now checking to ensure that we have considered all recent published materials. I thought it might be useful to identify that we have been involved in a number of evaluations...

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