Online First
February 28, 2022
- Original researchExtensive use of on-pack promotional claims on commercial baby foods in the UK
This study reports an online survey of promotional claims made on packaging of commercial baby foods. Claims were very common and often made to suggest foods were 'healthy'. The authors suggest regulation is needed to prevent inappropriate marketing
- Original researchTime to normalisation of tissue transglutaminase in paediatric coeliac disease is dependent on initial titre and half of patients will normalise within 12 months
This study explores the relationship of tissue transglutaminase antibody titres to symptoms and the time to normalisation in a cohort of patients with coeliac disease.
February 25, 2022
- Images in paediatricsStrabismus in juvenile hyperthyroidism: not just thyroid-associated ophthalmopathy
February 24, 2022
- Original researchVancomycin-associated acute kidney injury epidemiology in children: a systematic review
This systematic review concludes that the incidence of vancomycin-induced nephrotoxicity in children is relevant (11.8 %), so that caution during its use is warranted.
February 23, 2022
February 22, 2022
- Original researchCost-effectiveness of patient observation on cranial CT use with minor head trauma
Using a cohort of 18,471 children <18 years with Glasgow Coma Scale scores 14-15 presenting less than 24 hours after blunt head trauma, the authors estimated the cost-effectiveness of planned observation on the adjusted mean costs per child and CT use reduction. They found that planned ED observation in selected children with minor head trauma is cost-effective for reducing CT use for the PECARN intermediate-risk and high-risk categories.
February 21, 2022
- Paediatric Emergency MedicineExtra-axial haemorrhages in young children with skull fractures: abuse or accident?
An observational cohort study comparing extra-axial haemorrhages in children with a known accidental cause and known abusive causes.
February 17, 2022
- Original researchRate and severity of radiological features of physical abuse in children during the first UK-wide COVID-19 enforced national lockdown
There has been conflicting evidence on whether incidents of physical child abuse became more frequent during the 2020-21 Covid-related lockdowns. This study of abuse-related radiological investigations from hospitals in northern England revealed no such increase.
February 16, 2022
- Short reportEpidemiology and mapping of child road casualties
A short report presenting paediatric road traffic collision data from three sources in Wales. Compares reporting between datasets and discusses epidemiological factors associated with road traffic collisions.
- Original researchEvidence supporting safe diagnosis of coeliac disease in children with antitissue transglutaminase titre ≥5 times upper limit of normal
This single centre retrospective study of anti-tissue transglutaminase titres in children with coeliac disease suggests that there is greater scope for safe diagnosis without endoscopy and biopsy by reducing the cut off for antibody titre from the currently recommended level.
February 10, 2022
- Original researchData handling practices and commercial features of apps related to children: a scoping review of content analyses
A scoping review of apps related to children finds that data privacy and commercial features are rarely evaluated. These apps show frequent data sharing, manipulative delivery of In-app purchases and advertisements with content that is potentially harmful to child health.
February 07, 2022
- Original researchFive-year follow-up of new cases after a coeliac disease mass screening
This Swedish study of children screened for coeliac disease and followed up five years later showed that around a third with positive serology but normal biopsy had since developed coeliac disease. Conversely, very few children with negative serology became coeliac.
February 03, 2022
February 01, 2022
January 28, 2022
January 27, 2022
January 25, 2022
- Global child healthRandomised controlled trial of fosfomycin in neonatal sepsis: pharmacokinetics and safety in relation to sodium overload
A trial of Fosfamycin in combination with standard antibiotic therapy in newborn sepsis which established the dose that is appropriate in preterm and term neonates.
January 24, 2022
- Original researchDaytime urotherapy in nocturnal enuresis: a randomised, controlled trial
Daytime wetting is distressing to parents and children who can feel powerless to fix the problem. This randomised trial suggests for those whose problem is significant enough to reach secondary care detailed advice-giving isn't helpful and alarms should be used first-line.
January 21, 2022
January 19, 2022
January 10, 2022
December 30, 2021
December 21, 2021
December 20, 2021
December 17, 2021
- Original researchClinical impact of a gastrointestinal PCR panel in children with infectious diarrhoea
A prospective study of rapid PCR testing for stool pathogens in children with diarrhoea. Results were generally available two days more quickly than standard culture. This allowed more rational decisions about use of antibiotics in quarter of cases.
December 16, 2021
- Original researchCommunity health worker service delivery for maternal and child health: an observational study from Afghanistan
A population-based study using routinely gathered health services data in Afghanistan showed that the number of community health workers (CHW) and access to antenatal care by CHWs were relatively higher in remote areas than in less remote areas. The CHW program in Afghanistan contributes greatly to health care in remote communities.
December 10, 2021
- Short reportA new model to deliver scheduled outpatient care
Enhanced referral vetting and joint primary/secondary care paediatric clinics, delivered across clusters of networked primary care practice, are a feasible means of managing secondary care demand.
December 08, 2021
December 01, 2021
- Original researchInformed consent and assent guide for paediatric clinical trials in Europe
Young people and researchers gathered together to synthesise and rate the advice from all the EU systems they could find about paediatric clinical trials to create a simpler, patient-led, framework for information to aid meaningful trial consent discussions.
November 30, 2021
November 22, 2021
- Original researchIncome support for parents of children with chronic conditions and disability: where do we draw the line? A policy review
International comparisons of income support policies across seven nations show unemployed parents or carers of children with chronic conditions or disability qualified for 32 of the 58 policies. Most policies required a child tohave an impaired ability to function, not just a chronic condition or disability.
November 19, 2021
- Original researchAcceptability of different oral dosage forms in paediatric patients in hospital setting
Acceptability of medicines is routinely studied in Europe and North America, but there is little data from other nations. This study examines the acceptability of liquid and tablet forms of medicines in children in India, highlighting key challenges.
November 15, 2021
November 12, 2021
November 05, 2021
November 01, 2021
- ReviewClinical management of complex motor stereotypies
Children with repetitive abnormal movements are often referred to paediatric clinics and this paper is a helpful account of how to identify those that need further care with guidelines on assessment and management.
- Global child healthNational scale of neonatal CPAP to district hospitals in Malawi improves survival for neonates weighing between 1.0 and 1.3 kg
This paper demonstrates the effectiveness of a quality improvement program for the use of early CPAP among neonates weighing 1.0-1.3 kg in Malawi. This nurse-led CPAP program showed a significant improvement in mortality rates that was sustained during the follow-up period.