Footnotes

• X @M.bebars, @LankanMiller

• Contributors TR, JAAH and RV designed the project. FS, AOG and MAB undertook the literature review. FS wrote the manuscript with input from all co-authors. TR is the guarantor.

• Funding JAAH is funded by an Action Medical Research and British Paediatric Neurology Association Research Training Fellowship. This Fellowship has not specifically supported the manuscript and neither Action Medical Research or the British Paediatric Neurology Association have been involved in writing the manuscript.

• Competing interests JAAH is funded by an Action Medical Research and British Paediatric Neurology Association Research Training Fellowship. FS, AOG, MAB, RV and TR confirm that they have no conflicting interests.

• Provenance and peer review Not commissioned; externally peer-reviewed.